Nefopam, ¿un aliado en el manejo del dolor postoperatorio?

  • Camila Carrasco Chacon Residente  de Anestesiología y Reanimación.  Hospital Universitario Vall d’Hebron de Barcelona.
  • Anna Abad Torrent Vicepresidenta de GATIV. Servicio de Anestesiología y Reanimación. Hospital Universitario Vall d’Hebron de Barcelona.
Palabras clave: Nefopam, dolor, cirugia, anestesia, GATIV, Pain, Surgery, Anesthesia

Resumen

El Nefopam parece tener un papel en la analgesia multimodal. Se le atribuye un efecto ahorrador en el consumo de opiáceos postoperatorios. Asimismo, reduce la incidencia de náuseas, somnolencia y escalofríos mejorando el confort del paciente durante la primera fase de recuperación.

ABSTRACT

 Nefopam seems  to play a role  in multimodal analgesia. It is attributed a saving effect in the consumption of postoperative opiates. It also reduces the incidence of nausea, drowsiness and chills, which improves the patient's comfort during the first phase of recovery.

Citas

Choi SK, Yoon MH, Choi JI, Kim WM, Heo BH, Park KS, et al. Comparison of effects of intraoperative nefopam and ketamine infusion on managing postoperative pain after laparoscopic cholecystectomy administered remifentanil. Korean J Anesthesiol . 2016; 69:480 -6. (HTML)

Richebe P, Picard W, Rivat C, Jelacic S, Branchard O, Leproust S, et al. Effects of nefopam on early postoperative hyperalgesia after cardiac surgery. J Cardiothorac Vasc Anesth . 2013; 27:427. (PubMed)

Yoo JY, Lim BG, Kim H, Kong MH, Lee IO, Kim NS. The analgesic effect of nefopam combined with low dose remifentanil in patients undergoing middle ear surgery under desflurane anesthesia: a randomized controlled trial. Korean J Anesthesiol. 2015; 68:43-9. (HTML)

Mimoz O, Incagnoli P, Josse C, Gillon MC, Kuhlman L, Mirand A, et al. Analgesic efficacy and safety of nefopam vs. propacetamol following hepatic resection. Anaesthesia . 2001; 56:520 -5. (HTML)

Aymard G, Warot D, Demolis P, Giudicelli JF, Lechat P, Le Guern ME, et al . Comparative pharmacokinetics and pharmacodynamics of intravenous and oral nefopam in healthy volunteers. Pharmacol Toxicol . 2003; 92:279 (HTML)
Publicado
30-11-2018
Cómo citar
Carrasco Chacon, C., & Abad Torrent, A. (2018). Nefopam, ¿un aliado en el manejo del dolor postoperatorio?. Revista Electrónica AnestesiaR, 10(11), 2. https://doi.org/https://doi.org/10.30445/rear.v10i11.688

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