Nefopam, ¿un aliado en el manejo del dolor postoperatorio?
DOI:
https://doi.org/10.30445/rear.v10i11.688Palabras clave:
Nefopam, dolor, cirugia, anestesia, GATIVResumen
El Nefopam parece tener un papel en la analgesia multimodal. Se le atribuye un efecto ahorrador en el consumo de opiáceos postoperatorios. Asimismo, reduce la incidencia de náuseas, somnolencia y escalofríos mejorando el confort del paciente durante la primera fase de recuperación.
Citas
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Richebe P, Picard W, Rivat C, Jelacic S, Branchard O, Leproust S, et al. Effects of nefopam on early postoperative hyperalgesia after cardiac surgery. J Cardiothorac Vasc Anesth . 2013; 27:427. (PubMed)
Yoo JY, Lim BG, Kim H, Kong MH, Lee IO, Kim NS. The analgesic effect of nefopam combined with low dose remifentanil in patients undergoing middle ear surgery under desflurane anesthesia: a randomized controlled trial. Korean J Anesthesiol. 2015; 68:43-9. (HTML)
Mimoz O, Incagnoli P, Josse C, Gillon MC, Kuhlman L, Mirand A, et al. Analgesic efficacy and safety of nefopam vs. propacetamol following hepatic resection. Anaesthesia . 2001; 56:520 -5. (HTML)
Aymard G, Warot D, Demolis P, Giudicelli JF, Lechat P, Le Guern ME, et al . Comparative pharmacokinetics and pharmacodynamics of intravenous and oral nefopam in healthy volunteers. Pharmacol Toxicol . 2003; 92:279 (HTML)
Richebe P, Picard W, Rivat C, Jelacic S, Branchard O, Leproust S, et al. Effects of nefopam on early postoperative hyperalgesia after cardiac surgery. J Cardiothorac Vasc Anesth . 2013; 27:427. (PubMed)
Yoo JY, Lim BG, Kim H, Kong MH, Lee IO, Kim NS. The analgesic effect of nefopam combined with low dose remifentanil in patients undergoing middle ear surgery under desflurane anesthesia: a randomized controlled trial. Korean J Anesthesiol. 2015; 68:43-9. (HTML)
Mimoz O, Incagnoli P, Josse C, Gillon MC, Kuhlman L, Mirand A, et al. Analgesic efficacy and safety of nefopam vs. propacetamol following hepatic resection. Anaesthesia . 2001; 56:520 -5. (HTML)
Aymard G, Warot D, Demolis P, Giudicelli JF, Lechat P, Le Guern ME, et al . Comparative pharmacokinetics and pharmacodynamics of intravenous and oral nefopam in healthy volunteers. Pharmacol Toxicol . 2003; 92:279 (HTML)
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Publicado
2020-09-10
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Carrasco Chacon, C., & Abad Torrent, A. (2020). Nefopam, ¿un aliado en el manejo del dolor postoperatorio?. Revista Electrónica AnestesiaR, 10(11), 2. https://doi.org/10.30445/rear.v10i11.688
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