Nefopam: a partner in postopertive pain management?
DOI:
https://doi.org/10.30445/rear.v10i11.688Keywords:
Anesthesia, Surgery, Pain, GATIV, NefopamAbstract
Nefopam seems to play a role in multimodal analgesia. It is attributed a saving effect in the consumption of postoperative opiates. It also reduces the incidence of nausea, drowsiness and chills, which improves the patient's comfort during the first phase of recovery.
References
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Yoo JY, Lim BG, Kim H, Kong MH, Lee IO, Kim NS. The analgesic effect of nefopam combined with low dose remifentanil in patients undergoing middle ear surgery under desflurane anesthesia: a randomized controlled trial. Korean J Anesthesiol. 2015; 68:43-9. (HTML)
Mimoz O, Incagnoli P, Josse C, Gillon MC, Kuhlman L, Mirand A, et al. Analgesic efficacy and safety of nefopam vs. propacetamol following hepatic resection. Anaesthesia . 2001; 56:520 -5. (HTML)
Aymard G, Warot D, Demolis P, Giudicelli JF, Lechat P, Le Guern ME, et al . Comparative pharmacokinetics and pharmacodynamics of intravenous and oral nefopam in healthy volunteers. Pharmacol Toxicol . 2003; 92:279 (HTML)
Richebe P, Picard W, Rivat C, Jelacic S, Branchard O, Leproust S, et al. Effects of nefopam on early postoperative hyperalgesia after cardiac surgery. J Cardiothorac Vasc Anesth . 2013; 27:427. (PubMed)
Yoo JY, Lim BG, Kim H, Kong MH, Lee IO, Kim NS. The analgesic effect of nefopam combined with low dose remifentanil in patients undergoing middle ear surgery under desflurane anesthesia: a randomized controlled trial. Korean J Anesthesiol. 2015; 68:43-9. (HTML)
Mimoz O, Incagnoli P, Josse C, Gillon MC, Kuhlman L, Mirand A, et al. Analgesic efficacy and safety of nefopam vs. propacetamol following hepatic resection. Anaesthesia . 2001; 56:520 -5. (HTML)
Aymard G, Warot D, Demolis P, Giudicelli JF, Lechat P, Le Guern ME, et al . Comparative pharmacokinetics and pharmacodynamics of intravenous and oral nefopam in healthy volunteers. Pharmacol Toxicol . 2003; 92:279 (HTML)
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Published
2020-09-10
How to Cite
Carrasco Chacon, C., & Abad Torrent, A. (2020). Nefopam: a partner in postopertive pain management?. Revista Electrónica AnestesiaR, 10(11), 2. https://doi.org/10.30445/rear.v10i11.688
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