Neuromuscular blockers and respiratory distress syndrome.

Authors

  • María González Cofrade Resident doctor. Anesthesia Intensive Care Unit. Anesthesiology and Resuscitation Service. University Hospital 12 of October, Madrid, Spain.
  • Raquel García Álvarez Associate Physician. Anesthesia Intensive Care Unit. Anesthesiology and Resuscitation Service. University Hospital 12 of October, Madrid, Spain.

DOI:

https://doi.org/10.30445/rear.v12i8.845

Keywords:

anesthesia, neuromuscular blockers, adult respiratory distress syndrome

Abstract

Early use of neuromuscular blockers agents (NMBAs) in moderate-severe adult respiratory distress syndrome (ARDS) has previously been associated with a mortality decrease in the ACURASYS trial in 2010. However, the recently published ROSE study (Reevaluation of Systemic Early Neuromuscular Blockade) points out the disagreement with this practice. 

References

- Neuromuscular blockers in early acute respiratory distress syndrome. Papazian L, Forel JM, Gacouin A et al. N Engl J Med 2010; 363(12): 1107-16.

- Early neuromuscular blockade in the acute respiratory distress syndrome. Moss M et al. The National Heart, Lung and Blood Institute PETAL Clinical Trials Network. N Engl J Med 2019; 380: 1997-2008.

- Neuromuscular blocking agents for acute respiratory distress syndrome: how did we get conflicting results? Torbic H, Krishnan S, Duggal A. Crit Care 2019; 23 (1): 305.

- Akoumianaki E, Lyazidi A, Rey N, et al. Mechanical ventilation-induced reverse-triggered breaths: a frequently unrecognized form of neuromechanical coupling. Chest 2013;143:927-938.

- Guerin C, Reignier J, Richard JC et al. Prone positioning in severe acute respiratory distress syndrome. N Engl J Med 2013; 368: 2159-68.

Published

2020-09-10

How to Cite

González Cofrade, M., & García Álvarez, R. (2020). Neuromuscular blockers and respiratory distress syndrome. Revista Electrónica AnestesiaR, 12(8), 1. https://doi.org/10.30445/rear.v12i8.845

Issue

Section

Critical reviews of articles