Are there prognostic factors for mortality in the septic patient in the ICU? The value of the serum lactate elimination rate
DOI:
https://doi.org/10.30445/rear.v12i4.809Keywords:
lactate elimination rate, lactate, mortality, septic shock, prognostic factorAbstract
Sepsis is the first cause of death due to infection in the world and the prognosis is time dependent on effective treatment. There are numerous prognostic factors described in the literature, however there are just a few studies comparing them among them to assess if there is one with greater weight compared to others. The present article, with a sample of 82 patients, analyzes different prognostic factors in the first 24 hours of admission as survival indicators at 28 days. These are: lactate numbers, their elimination rate, central venous saturation and the difference between central arteriovenous oxygen saturation. The results show that the lactate levels at 24 hours are the ones with higher sensitivity-specificity (cut-off point of 2.15 mmol / dl), followed by the lactate levels at 12 and at 6 hours.
References
- Cecconi M, Evans L, Levy M, Rhodes A. Sepsis and septic shock. Lancet. 2018 Jul 7;392(10141):75-87. doi: 10.1016/S0140-6736(18)30696-2. Epub 2018 Jun 21. Review.
- Guo Y, Yang H, Gao W, Ma CE, Li T. Combination of Biomarkers in Predicting 28-Day Mortality for Septic Patients. J Coll Physicians Surg Pak. 2018 Sep;28(9):672-676. doi: 10.29271/jcpsp.2018.09.672.
- He H, Long Y, Liu D, Wang X, Tang B. The Prognostic Value of Central Venous-to-Arterial CO2 Difference/Arterial-Central Venous O2 Difference Ratio in Septic Shock Patients with Central Venous O2 Saturation ≥80. Shock. 2017 Nov;48(5):551-557. doi: 10.1097/SHK.0000000000000893.
- Bhat SR, Swenson KE, Francis MW, Wira CR. Lactate Clearance Predicts Survival Among Patients in the Emergency Department with Severe Sepsis. West J Emerg Med. 2015 Dec;16(7):1118-26. doi: 10.5811/westjem.2015.10.27577. Epub 2015 Dec 8.
- Lokhandwala S, Andersen LW, Nair S, Patel P, Cocchi MN, Donnino MW. Absolute lactate value vs relative reduction as a predictor of mortality in severe sepsis and septic shock. J Crit Care. 2017 Feb;37:179-184. doi: 10.1016/j.jcrc.2016.09.023. Epub 2016 Oct 6.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2020 Revista Electrónica AnestesiaR
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Envío y derechos de autor