Maintenance of the therapy with beta blockers in sepsis

Authors

  • Raquel García Álvarez Servicio de Anestesiología y Reanimación. Hospital Universitario 12 de Octubre. Madrid
  • Pablo López-Arcas Calleja MIR. Servicio de Anestesiología y Reanimación. Hospital Universitario 12 de Octubre. Madrid
  • Isabel de la Calle Servicio de Anestesiología y Reanimación. Hospital Universitario 12 de Octubre. Madrid
  • Eloisa López López Jefe de Sección. Servicio de Anestesiología y Reanimación. Hospital Universitario 12 de Octubre. Madrid

DOI:

https://doi.org/10.30445/rear.v10i6.458

Keywords:

ICU, critical, beta-blocker, septic shock, sepsis

Abstract

There is some growing evidence now that beta-blocker therapy (BB) may bring benefits for some patients with sepsis because it reduces the andrenergic response for stress. What it´s still unknown is the effect of  maintenance of the therapy during the acute phase of sepsis; there´s no  recommendation from clinic guidelines at this point. 

References

1. Sanfilippo F, Santonocito C, Morelli A, Foex P. Beta-blocker use in severe sepsis and septic shock: a systematic review. Curr Med Res Opin 2015; 31(10): 1817-25.
2. Morelli A, Ertmer C, Westphal M, Rehberg S, Kampmeier T, Ligges S, et al. Effect of heart rate control with esmolol on hemodynamic and clinical outcomes in patients with septic shock: A randomized clinical trial. JAMA. 2013;310:1683-91.
3. Macchia A, Romero M, Comignani PD. Previous prescription of β-blockers is associated with reduced mortality among patients hospitalized in intensive care units for sepsis. Critical Care Medicine. 40(10):2768-72. 2012.
4. Rhodes A et al. Surviving Sepsis Campaign: International guidelines for management of sepsis and septic shock: 2016. Intensive Care Med 2017; 43(3): 304-377.
5. Hennessy E, Adams C, Reen FJ, O’Gara F. Is there potential for repurposing statins as novel antimicrobials? Antimicrob Agents Chemother 2016; 60(9): 5111-21.

Published

2020-09-10

How to Cite

García Álvarez, R., López-Arcas Calleja, P., de la Calle, I., & López López, E. (2020). Maintenance of the therapy with beta blockers in sepsis. Revista Electrónica AnestesiaR, 10(6), 5. https://doi.org/10.30445/rear.v10i6.458

Issue

Section

Critical reviews of articles