Adamgammadex
DOI:
https://doi.org/10.30445/rear.v16i12.1295Keywords:
Adamgammadex, Rocuronium, neuromuscular block, reversalAbstract
Adamgammadex is a new agent for reversing neuromuscular blockade induced by rocuronium or vecuronium. Due to its higher molecular weight, it requires a higher dose than sugammadex. Clinical studies in China suggest that it is well tolerated and comparable to sugammadex in recovering a TOF ratio ≥ 0.9 within 5 minutes, with fewer adverse effects such as anaphylaxis, recurarisation, bradycardia, and laryngospasm. However, further studies are needed to confirm its efficacy and safety.
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