Prophylactic use Tranexamic Acid in the prevention of postpartum hemorrhage
DOI:
https://doi.org/10.30445/rear.v14i6.1070Keywords:
Postpartum Hemorrhage, Tranexamic Acid, Fibrinolysis, Antifibrinolytic Agents, Drug Therapy, MortalityAbstract
Introduction: Postpartum hemorrhage is the leading cause of maternal death. The incidence of this complication is between 6% to 10% in all births. Postpartum hemorrhage is related to multiple maternal and fetal factors. The approach is multidisciplinary, it begins with prevention and clinical evaluation without delaying the
appropriate approach. In pharmacological management, tranexamic acid is a useful and effective fibrinolytic agent in reducing bleeding in vaginal deliveries and cesarean sections. The objective is to carry out a literature review no systematic on the prophylactic use of tranexamic acid in the prevention of postpartum hemorrhage. Material and methods: A literature search was carried out in the PubMed and Scielo databases for uptated abd relevant articles and relevant articles in English or Spanish, presenting the importance of the prevention, diagnosis and pharmacological management. Conclusion: Postpartum haemorrhage is a complication with high maternal mortality, for which intrahospital strategies and protocols and tranexamic acid is an important alternative with favorable results, suggesting its prophylactic use in these type of patients with different drug considerations and some adverse effects.
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