Hyperthermia associated with dexmedetomidine

Authors

  • Esmeralda Soto Garrucho Resident of Anesthesiology and Resuscitation. Valme University Hospital, Seville. Spain.
  • María Dulce Moreno Rey Deputy of the Anesthesiology and Resuscitation Service. Valme University Hospital, Seville. Spain.
  • Mercedes Echevarría Moreno Head of Anesthesiology Service. Director of the U.G.C Anesthesiology and Resuscitation. Valme University Hospital, Seville. Spain.

DOI:

https://doi.org/10.30445/rear.v14i10.1065

Keywords:

Dexmedetomina; efectos adversos; sedación; cuidados críticos

Abstract

Dexmedetomidine is an α2 agonist drug used as an anxiolytic and sedative in patients in Intensive Care Units (ICU) and Resuscitation Units (REA). Its most frequent adverse effects are bradycardia and hypotension, but given the increasing use of this drug, hyperthermia refractory to antipyretic therapy has been discovered. Its diagnosis is one of exclusion after ruling out other possible etiologies of hyperthermia such as infections, drugs...etc. With this clinical case, we want to promote the study of the prevalence, risk factors and triggers of this adverse effect.

 

References

- https://cima.aemps.es/cima/dochtml/ft/82586/FT_82586.html

- Patel RA, fiebre de Gallagher JCDrug. Farmacoterapia. 2010; 30: 57–69.

- Krüger, Bernard D. MD*; Kurmann, Judith MM*; Corti, Natascia MD†; Spahn, Donat R. MD*; Bettex, Dominique MD*; Rudiger, Alain MD* Dexmedetomidine-Associated Hyperthermia: A Series of 9 Cases and a Review of the Literature, Anesthesia & Analgesia: December 2017 - Volume 125 - Issue 6

- Grayson, K. D., Tobin, A., Lim, D. K., Reid, D., & Ghani, M. (2017). Dexmedetomidine-associated hyperthermia: A retrospective cohort study of intensive care unit admissions between 2009 and 2016. Anaesthesia and Intensive Care, 45(6), 727–736.

- Faust, A. C., & Sutton, S. E. (2015). Dexmedetomidine-associated fever in the intensive care unit. Therapeutic advances in drug safety, 6(6), 234–237.

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Published

2022-11-07

How to Cite

Soto Garrucho, E., Moreno Rey, M. D., & Echevarría Moreno, M. (2022). Hyperthermia associated with dexmedetomidine. Revista Electrónica AnestesiaR, 14(10). https://doi.org/10.30445/rear.v14i10.1065

Issue

Vol. 14 No. 10 (2022): Revista Electrónica de AnestesiaR

Section

Clinical case reports

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